Idioma:

Cardiorespiratory and anesthetic effects of propofol and thiopental in dogs

Quandt, J.E. (University of Georgia, Athens, GA.) ; Robinson, E.P ; Rivers, W.J ; Raffe, M.R

American journal of veterinary research, 1998-09, Vol.59 (9), p.1137-1143 [Periódico revisado por pares]

United States

Sem texto completo

Citações Citado por

Enviar para

Título:
Cardiorespiratory and anesthetic effects of propofol and thiopental in dogs
Autor: Quandt, J.E. (University of Georgia, Athens, GA.) ; Robinson, E.P ; Rivers, W.J ; Raffe, M.R
Assuntos: ADVERSE EFFECTS ; ANAESTHESIA ; ANESTESIA ; ANESTHESIE ; Anesthetics, Intravenous - pharmacology ; Animals ; BLOOD GASES ; BLOOD PRESSURE ; Blood Pressure - drug effects ; CARBON DIOXIDE ; Cardiac Output - drug effects ; CARDIAC RHYTHM ; CHIEN ; Cross-Over Studies ; DIOXIDO DE CARBONO ; DIOXYDE DE CARBONE ; DOGS ; Dogs - physiology ; DRUGS ; EFECTOS SECUNDARIOS ; EFFET SECONDAIRE ; Female ; FRECUENCIA CARDIACA ; FREQUENCE CARDIAQUE ; GASES SANGUINEOS ; GAZ SANGUIN ; Heart - drug effects ; HEART RATE ; Male ; MEDICAMENT ; MEDICAMENTOS ; PERRO ; PRESION SANGUINEA ; PRESSION SANGUINE ; Propofol - pharmacology ; RECOVERY ; Reference Values ; REFLEXES ; RESPIRACION ; RESPIRATION ; Respiration - drug effects ; RESPIRATION RATE ; SIDE EFFECTS ; TASA DE RESPIRACION ; TAUX DE RESPIRATION ; THIOPENTAL ; Thiopental - pharmacology ; TIDAL VOLUME ; Tidal Volume - drug effects ; TIOPENTAL
É parte de: American journal of veterinary research, 1998-09, Vol.59 (9), p.1137-1143
Notas: L70
1997095137
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
ObjectType-News-3
content type line 23
Descrição: To compare cardiorespiratory and anesthesia effects of IV administered propofol and thiopental in dogs. 6 healthy mixed-breed dogs. Each dog was anesthetized with isoflurane, then a thermistor catheter was inserted in the pulmonary artery. After a minimum of 2.5 hours of recovery, a catheter was placed in a cephalic vein for administration of lactated Ringer's solution and drugs. Propofol (8 mg/kg of body weight) or thiopental (19.4 mg/kg) was administered to each dog in a randomized crossover design study. All dogs were intubated and allowed to breathe 100% oxygen spontaneously. Heart rate and rhythm; systolic, diastolic, and mean arterial blood pressures; respiratory rate; end-tidal carbon dioxide concentration; tidal volume; and reflexes (toe web pinch, palpebral response, and jaw tone) were measured before and every 2 minutes for the first 10 minutes, then at 15, 30, and 60 minutes after drug administration. Cardiac output was determined at 0, 2, 6, 10, 15, 30, and 60 minutes, and blood samples were collected at 0, 2, 10, and 30 minutes. Time to endotracheal extubation, head lift, and ability to sit sternally and walk unaided were recorded. 3 of 6 dogs in each group were apneic after drug administration. Reflexes were decreased similarly for both anesthetic agents, but were not completely lost. Time to sternal position and walking unaided were significantly shorter in response to propofol. Anesthesia was rapid; however, respiratory depression and apnea were major adverse effects associated with propofol and thiopental. Propofol has the advantage of inducing rapid, coordinated anesthesia recovery.
Editor: United States
Idioma: Inglês

Links

View this record in MEDLINE/PubMed

Voltar para lista de resultados

Realização: Logos de Redes Sociais:

Cardiorespiratory and anesthetic effects of propofol and thiopental in dogs

Quandt, J.E. (University of Georgia, Athens, GA.) ; Robinson, E.P ; Rivers, W.J ; Raffe, M.R

United States

Buscando em bases de dados remotas. Favor aguardar.