skip to main content
Idioma:
Primo Search
Clear Search Box
Search in: Busca Geral
Busca Avançada
Busca por Índices

Residual neuromuscular blockade in the postanesthesia care unit: observational cross-sectional study of a multicenter cohort

Errando, Carlos L ; Garutti, Ignacio ; Mazzinari, Guido ; Díaz-Cambronero, Óscar ; Bebawy, John F

Minerva anestesiologica, 2016-12, Vol.82 (12), p.1267-1277

Italy

Texto completo disponível

Citações Citado por
  • Título:
    Residual neuromuscular blockade in the postanesthesia care unit: observational cross-sectional study of a multicenter cohort
  • Autor: Errando, Carlos L ; Garutti, Ignacio ; Mazzinari, Guido ; Díaz-Cambronero, Óscar ; Bebawy, John F
  • Assuntos: Androstanols ; Anesthesia Recovery Period ; Cross-Sectional Studies ; Delayed Emergence from Anesthesia - epidemiology ; Delayed Emergence from Anesthesia - etiology ; Female ; gamma-Cyclodextrins - therapeutic use ; Humans ; Male ; Neostigmine - therapeutic use ; Neuromuscular Nondepolarizing Agents ; Prospective Studies ; Sex Factors ; Spain - epidemiology ; Young Adult
  • É parte de: Minerva anestesiologica, 2016-12, Vol.82 (12), p.1267-1277
  • Notas: ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-3
    content type line 23
    ObjectType-Undefined-2
  • Descrição: Residual neuromuscular blockade after general anesthesia using nondepolarizing neuromuscular blocking agents has pathophysiological, clinical, and economic consequences. A significant number of patients under muscle relaxation sustain residual curarization. Observational, prospective, multicenter study of a cohort of patients (Residual Curarization in Spain Study, ReCuSS). Residual blockade was defined as TOFr<0.9. Patients >18 years-old under general anesthesia, including at least one dose of non-depolarizing neuromuscular blocking agents, and transferred extubated and spontaneously ventilating to the postanesthesia care unit were included. Pre- and intraoperative data were recorded, including, patient characteristics, ASA physical status, experience of the anesthesiologist, type of surgery, temperature monitoring, surgery duration, neuromuscular blockade-related parameters, type of anesthesia (halogenated-balanced, intravenous propofol-based, other), and use of neuromuscular monitoring. A total of 763 patients from 26 hospitals were included, 190 patients (26.7%) showing residual paralysis. Female patients were more prone to residual neuromuscular blockade. Length of surgery, type of relaxant used (benzylisoquinolines), halogenated anesthesia, absence of intraoperative specific monitoring, avoidance of drug reversal, and neostigmine reversal (vs. sugammadex), were significantly related to residual blockade. In the postanesthesia care unit, patients with residual neuromuscular blockade had an increased incidence of respiratory events and tracheal reintubation. The incidence of residual blockade in Spain is similar to that published in other settings and countries. Female gender, longer duration of surgery, and halogenated drugs for anesthesia maintenance were related to residual paralysis, as were NMBA specific items, such as the use of benzylisoquinoline drugs, and the absence of reversal or reversal with neostigmine.
  • Editor: Italy
  • Idioma: Inglês
Links
Voltar para lista de resultados

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

Buscando em bases de dados remotas. Favor aguardar.