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Molecular cloning of a gene encoding a Chlamydia psittaci 57‐kDa protein that shares antigenic determinants with ca. 60‐kDa proteins present in many Gram‐negative bacteria

Menozzi, Franco D. ; Menozzi‐Dejaiffe, Catherine ; Nano, Francis E.

FEMS microbiology letters, 1989-03, Vol.58 (1), p.59-63 [Periódico revisado por pares]

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Título:
Molecular cloning of a gene encoding a Chlamydia psittaci 57‐kDa protein that shares antigenic determinants with ca. 60‐kDa proteins present in many Gram‐negative bacteria
Autor: Menozzi, Franco D. ; Menozzi‐Dejaiffe, Catherine ; Nano, Francis E.
Assuntos: Bacteriology ; Biological and medical sciences ; Chlamydia psittaci ; Escherichia coli ; Fundamental and applied biological sciences. Psychology ; Genetics ; Microbiology ; Recombinant antigens
É parte de: FEMS microbiology letters, 1989-03, Vol.58 (1), p.59-63
Notas: Department of Biochemistry and Microbiology, University of Victoria, Victoria, B.C., V8W 2Y2, Canada.
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Descrição: In order to develop reagents to study the immune response of guinea pigs to infection by Chlamydia psittaci guinea pig inclusion conjunctivitis strain (GPIC), we constructed a plasmid clone bank with C. psittaci DNA. One of the recombinant clones isolated produced large amounts of a 57‐kilodalton (kDa) protein that was immunoreactive with sera from GPIC infected guinea pigs. While investigating this recombinant protein, we discovered that all the Gram‐negative bacteria analyzed so far have immunoreactive proteins of similar size. This protein seems to be a ‘common antigen’ already described in various Gram‐negative bacteria.
Editor: Oxford, UK: Blackwell Publishing Ltd
Idioma: Inglês

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