skip to main content
Idioma:
Primo Search
Clear Search Box
Search in: Busca Geral
Busca Avançada
Busca por Índices

Preprocedural platelet transfusion for patients with thrombocytopenia undergoing interventional radiology procedures is not associated with reduced bleeding complications

Warner, Matthew A. ; Woodrum, David ; Hanson, Andrew ; Schroeder, Darrell R. ; Wilson, Gregory ; Kor, Daryl J.

Transfusion (Philadelphia, Pa.), 2017-04, Vol.57 (4), p.890-898 [Periódico revisado por pares]

United States: Wiley Subscription Services, Inc

Texto completo disponível

Citações Citado por
  • Título:
    Preprocedural platelet transfusion for patients with thrombocytopenia undergoing interventional radiology procedures is not associated with reduced bleeding complications
  • Autor: Warner, Matthew A. ; Woodrum, David ; Hanson, Andrew ; Schroeder, Darrell R. ; Wilson, Gregory ; Kor, Daryl J.
  • Assuntos: Adult ; Aged ; Erythrocyte Transfusion ; Female ; Hemorrhage - diagnostic imaging ; Hemorrhage - etiology ; Hemorrhage - therapy ; Humans ; Male ; Middle Aged ; Platelet Transfusion ; Preoperative Care ; Radiography, Interventional ; Retrospective Studies ; Thrombocytopenia - complications ; Thrombocytopenia - diagnostic imaging ; Thrombocytopenia - therapy
  • É parte de: Transfusion (Philadelphia, Pa.), 2017-04, Vol.57 (4), p.890-898
  • Notas: This study was made possible by funding from the Mayo Clinic Department of Anesthesiology and the Critical Care Integrated Multidisciplinary Practice, Rochester, MN. In addition, this study was supported by an NIH R01 grant (HL121232) to DJK.
    ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-2
    content type line 23
  • Descrição: BACKGROUND Platelet (PLT) transfusion before interventional radiology procedures is commonly performed in patients with thrombocytopenia. However, it is unclear if PLT transfusion is associated with reduced bleeding complications. STUDY DESIGN AND METHODS This is a retrospective cohort study of adults undergoing interventional radiology procedures between January 1, 2009, and December 31, 2013. Baseline characteristics, coagulation variables, transfusion requirements, and procedural details were evaluated. Propensity‐matched analyses were used to assess relationships between PLT transfusions and the outcomes of interest, including a primary outcome of periprocedural red blood cell (RBC) transfusion during the procedure or within the first 24 hours after procedure. RESULTS A total of 18,204 participants met inclusion criteria, and 2060 (11.3%) had a PLT count of not more than 100 × 109/L before their procedure. Of these, 203 patients (9.9) received preprocedural PLTs. There was no significant difference in RBC requirements between those receiving or not receiving preprocedural PLTs in propensity‐matched analysis (odds ratio [OR], 1.45; 95% confidence interval [CI], 0.95‐2.21; p = 0.085). PLT transfusion was associated with increased rates of intensive care unit admission (OR [95% CI], 1.57 [1.07‐2.32]; p = 0.022). CONCLUSION In patients with thrombocytopenia undergoing interventional radiology procedures, preprocedural PLT transfusion was not associated with reduced periprocedural RBC requirements. These findings suggest that prophylactic PLT transfusions are not warranted in nonbleeding patients with preprocedural PLT counts exceeding 50 × 109/L. Future clinical trials are needed to further define relationships between prophylactic PLT administration and bleeding complications, especially at more severe levels of thrombocytopenia or in the presence of PLT dysfunction.
  • Editor: United States: Wiley Subscription Services, Inc
  • Idioma: Inglês
Links
Voltar para lista de resultados

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

Buscando em bases de dados remotas. Favor aguardar.