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The effect of flour from the rind of the yellow passion fruit on glycemic control of people with diabetes mellitus type 2: a randomized clinical trial

de Araújo, Márcio Flávio Moura ; Veras, Vivian Saraiva ; de Freitas, Roberto Wagner Júnior Freire ; de Paula, Maria do Livramento ; de Araújo, Thiago Moura ; Uchôa, Lilian Raquel Alexandre ; Gaspar, Maria Wendiane Gueiros ; Cunha, Maria da Conceição do Santos Oliveira ; Serra, Maria Aparecida Alves de Oliveira ; Carvalho, Carolina Maria de Lima ; Costa, Edmara Chaves ; Damasceno, Marta Maria Coelho

Journal of diabetes and metabolic disorders, 2017-04, Vol.16 (1), p.18-18, Article 18 [Periódico revisado por pares]

London: BioMed Central

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Título:
The effect of flour from the rind of the yellow passion fruit on glycemic control of people with diabetes mellitus type 2: a randomized clinical trial
Autor: de Araújo, Márcio Flávio Moura ; Veras, Vivian Saraiva ; de Freitas, Roberto Wagner Júnior Freire ; de Paula, Maria do Livramento ; de Araújo, Thiago Moura ; Uchôa, Lilian Raquel Alexandre ; Gaspar, Maria Wendiane Gueiros ; Cunha, Maria da Conceição do Santos Oliveira ; Serra, Maria Aparecida Alves de Oliveira ; Carvalho, Carolina Maria de Lima ; Costa, Edmara Chaves ; Damasceno, Marta Maria Coelho
Assuntos: Analysis ; Clinical trials ; Control ; Diabetes ; Dietary supplements ; Endocrinology ; Glucose ; Health care ; Insulin ; Medicine ; Medicine & Public Health ; Metabolic Diseases ; Metabolism ; Natural products ; Nurses ; Passion fruit ; Physiological aspects ; Primary care ; Research Article ; Standard deviation ; Studies ; Type 2 diabetes
É parte de: Journal of diabetes and metabolic disorders, 2017-04, Vol.16 (1), p.18-18, Article 18
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Descrição: Background The single or combined use of herbal and dietary products with medications has shown benefits in the metabolic modulation of carbohydrates, in the restoring of the function of pancreatic beta cells, and in insulin resistance. To analyze the effect of the use of flour made from the rind of the yellow passion fruit on the glycemic control of people with diabetes mellitus type 2. Methods An open, prospective, randomized clinical trial was undertaken with 54 participants over an eight-week period. The participants from the case group were advised to ingest 12 g of the flour, three times daily; before breakfast, lunch and dinner. Results After eight weeks of use of the flour made from the rind of the yellow passion fruit, we did not identify significant statistical differences in the values for capillary blood glucose ( p = 0.562), fasting blood glucose ( p = 0.268) or glycated hemoglobin ( p = 0.229) between the study groups. In the case group, we identified an increase (29.6%–37%) of the people with normal HbA1 c ; however, this did not have statistical relevance ( p = 0.274). Discussion Based in our findings, we believe it is important to extend the time of exposure to the intervention and increase the rigor in the monitoring of adherence in future studies on this topic. Only in this way will we be able to make confident inferences in relation to the use of flour made from the rind of theyellow passion fruit as a therapeutic tool for glycemic and/or metabolic control in persons with DM 2. Conclusions In the sample in question, the use of the flour made from the rind of the yellow passion fruit, over an eight-week period, did not improve the glycemic control of people with type 2 diabetes. Trial registration: U1111.1187.3616. Registered 6 September, retrospectively registered, in the Brazilian Clinical Trials Registry.
Editor: London: BioMed Central
Idioma: Inglês

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The effect of flour from the rind of the yellow passion fruit on glycemic control of people with diabetes mellitus type 2: a randomized clinical trial

London: BioMed Central

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