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Five-year follow-up of angiographic disease progression after medicine, angioplasty, or surgery

Borges, Jorge Chiquie ; Lopes, Neuza ; Soares, Paulo R ; Góis, Aécio F T ; Stolf, Noedir A ; Oliveira, Sergio A ; Hueb, Whady A ; Ramires, Jose A F

Journal of cardiothoracic surgery, 2010-10, Vol.5 (1), p.91-91, Article 91 [Periódico revisado por pares]

England: BioMed Central

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  • Título:
    Five-year follow-up of angiographic disease progression after medicine, angioplasty, or surgery
  • Autor: Borges, Jorge Chiquie ; Lopes, Neuza ; Soares, Paulo R ; Góis, Aécio F T ; Stolf, Noedir A ; Oliveira, Sergio A ; Hueb, Whady A ; Ramires, Jose A F
  • Assuntos: Angioplasty, Balloon, Coronary ; Cardiology ; Cardiovascular disease ; Coronary Angiography ; Coronary Artery Bypass ; Coronary Artery Disease - diagnostic imaging ; Coronary Artery Disease - surgery ; Coronary Artery Disease - therapy ; Coronary vessels ; Disease Progression ; Female ; Follow-Up Studies ; Heart attacks ; Humans ; Hypolipidemic Agents - therapeutic use ; Male ; Middle Aged ; Prognosis
  • É parte de: Journal of cardiothoracic surgery, 2010-10, Vol.5 (1), p.91-91, Article 91
  • Notas: ObjectType-Article-2
    SourceType-Scholarly Journals-1
    ObjectType-News-1
    ObjectType-Feature-3
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  • Descrição: Progression of atherosclerosis in coronary artery disease is observed through consecutive angiograms. Prognosis of this progression in patients randomized to different treatments has not been established. This study compared progression of coronary artery disease in native coronary arteries in patients undergoing surgery, angioplasty, or medical treatment. Patients (611) with stable multivessel coronary artery disease and preserved ventricular function were randomly assigned to CABG, PCI, or medical treatment alone (MT). After 5-year follow-up, 392 patients (64%) underwent new angiography. Progression was considered a new stenosis of ≥ 50% in an arterial segment previously considered normal or an increased grade of previous stenosis > 20% in nontreated vessels. Of the 392 patients, 136 underwent CABG, 146 PCI, and 110 MT. Baseline characteristics were similar among treatment groups, except for more smokers and statin users in the MT group, more hypertensives and lower LDL-cholesterol levels in the CABG group, and more angina in the PCI group at study entry. Analysis showed greater progression in at least one native vessel in PCI patients (84%) compared with CABG (57%) and MT (74%) patients (p < 0.001). LAD coronary territory had higher progression compared with LCX and RCA (P < 0.001). PCI treatment, hypertension, male sex, and previous MI were independent risk factors for progression. No statistical difference existed between coronary events and the development of progression. The angioplasty treatment conferred greater progression in native coronary arteries, especially in the left anterior descending territories and treated vessels. The progression was independently associated with hypertension, male sex, and previous myocardial infarction.
  • Editor: England: BioMed Central
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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