Idioma:

Validation of a gas chromatographic method to quantify sesquiterpenes in copaiba oils

Sousa, João Paulo B. ; Brancalion, Ana P.S. ; Souza, Ariana B. ; Turatti, Izabel C.C. ; Ambrósio, Sérgio R. ; Furtado, Niege A.J.C. ; Lopes, Norberto P. ; Bastos, Jairo K.

Journal of pharmaceutical and biomedical analysis, 2011-03, Vol.54 (4), p.653-659 [Periódico revisado por pares]

Amsterdam: Elsevier B.V

Texto completo disponível

Citações Citado por

Enviar para

Título:
Validation of a gas chromatographic method to quantify sesquiterpenes in copaiba oils
Autor: Sousa, João Paulo B. ; Brancalion, Ana P.S. ; Souza, Ariana B. ; Turatti, Izabel C.C. ; Ambrósio, Sérgio R. ; Furtado, Niege A.J.C. ; Lopes, Norberto P. ; Bastos, Jairo K.
Assuntos: Analysis ; Analytical, structural and metabolic biochemistry ; Anti-Inflammatory Agents, Non-Steroidal - chemistry ; Balsams - chemistry ; beta-caryophyllene ; Biological and medical sciences ; Copaifera ; Copaifera species ; detection limit ; essential oils ; Fabaceae - chemistry ; Flame Ionization - methods ; Fundamental and applied biological sciences. Psychology ; gas chromatography ; Gas Chromatography-Mass Spectrometry ; General pharmacology ; glass ; Limit of Detection ; Medical sciences ; Medicine, Traditional ; oils ; Oils, Volatile - chemistry ; Oleoresins ; pharmaceutical industry ; Pharmacology. Drug treatments ; Quality Control ; Reproducibility of Results ; Sesquiterpenes ; Sesquiterpenes - analysis ; Statistics as Topic ; Technology, Pharmaceutical ; traditional medicine ; Validated analytical method
É parte de: Journal of pharmaceutical and biomedical analysis, 2011-03, Vol.54 (4), p.653-659
Notas: http://dx.doi.org/10.1016/j.jpba.2010.10.006
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: Copaifera species (Leguminoseae) are popularly known as “copaiba” or “copaíva”. The oleoresins obtained from the trunk of these species have been extensively used in folk medicine and are commercialized in Brazil as crude oil and in several pharmaceutical and cosmetic products. This work reports a complete validated method for the quantification of β-caryophyllene, α-copaene, and α-humulene in distinct copaiba oleoresins available commercially. Thus, essential oil samples (100μL) were dissolved in 20mL of hexanes containing internal standard (1,2,4,5-tetramethylbenzene, 3.0mM) in a 25mL glass flask. A 1μL aliquot was injected into the GC-FID system. A fused-silica capillary column HP-5, coated with 5% phenyl-methylsiloxane was used for this study. The developed method gave a good detection response with linearity in the range of 0.10–18.74mM. Limits of detection and quantitation variety ranged between 0.003 and 0.091mM. β-Caryophyllene, α-copaene, and α-humulene were recovered in a range from 74.71% to 88.31%, displaying RSD lower than 10% and relative errors between −11.69% and −25.30%. Therefore, this method could be considered as an analytical tool for the quality control of different Copaifera oil samples and its products in both cosmetic and pharmaceutical companies.
Editor: Amsterdam: Elsevier B.V
Idioma: Inglês

Links

Voltar para lista de resultados

Realização: Logos de Redes Sociais:

Validation of a gas chromatographic method to quantify sesquiterpenes in copaiba oils

Sousa, João Paulo B. ; Brancalion, Ana P.S. ; Souza, Ariana B. ; Turatti, Izabel C.C. ; Ambrósio, Sérgio R. ; Furtado, Niege A.J.C. ; Lopes, Norberto P. ; Bastos, Jairo K.

Amsterdam: Elsevier B.V

Buscando em bases de dados remotas. Favor aguardar.