Idioma:

Randomized controlled trial using vitamins E and D supplementation in atopic dermatitis

Javanbakht, Mohammad Hassan ; Keshavarz, Seyed Ali ; Djalali, Mahmoud ; Siassi, Fereydoun ; Eshraghian, Mohammad Reza ; Firooz, Alireza ; Seirafi, Hassan ; Ehsani, Amir Hooshang ; Chamari, Maryam ; Mirshafiey, Abbas

The Journal of dermatological treatment, 2011-06, Vol.22 (3), p.144-150 [Periódico revisado por pares]

Oslo: Informa Healthcare USA on behalf of Informa UK Ltd

Texto completo disponível

Citações Citado por

Enviar para

Título:
Randomized controlled trial using vitamins E and D supplementation in atopic dermatitis
Autor: Javanbakht, Mohammad Hassan ; Keshavarz, Seyed Ali ; Djalali, Mahmoud ; Siassi, Fereydoun ; Eshraghian, Mohammad Reza ; Firooz, Alireza ; Seirafi, Hassan ; Ehsani, Amir Hooshang ; Chamari, Maryam ; Mirshafiey, Abbas
Assuntos: Allergic diseases ; alpha-Tocopherol - blood ; atopic dermatitis ; Biological and medical sciences ; Dermatitis, Atopic - drug therapy ; Dermatitis, Atopic - pathology ; Dietary Supplements ; Double-Blind Method ; Female ; Humans ; Immunopathology ; Male ; Medical sciences ; SCORAD ; Skin allergic diseases. Stinging insect allergies ; vitamin D ; Vitamin D - analogs & derivatives ; Vitamin D - blood ; Vitamin D - therapeutic use ; vitamin E ; Vitamin E - therapeutic use
É parte de: The Journal of dermatological treatment, 2011-06, Vol.22 (3), p.144-150
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-News-1
ObjectType-Feature-3
content type line 23
Descrição: Abstract Background: Atopic dermatitis is a chronically relapsing, highly pruritic and inflammatory skin disease. This study was done to assess the effects of vitamins D and E supplementation on the clinical manifestation of atopic dermatitis. Methods: Forty-five atopic dermatitis patients were included in a randomized, double-blind, placebo-controlled trial. They were randomly divided into four groups and treated for 60 days: group P (n = 11), vitamins D and E placebos; group D (n = 12), 1600 IU vitamin D3 plus vitamin E placebo; group E (n = 11), 600 IU synthetic all-rac-α-tocopherol plus vitamin D placebo; and group DE (n = 11), 1600 IU vitamin D3 plus 600 IU synthetic all-rac-α-tocopherol. Serum 25(OH) vitamin D and plasma α-tocopherol were determined before and after the trial. The clinical improvement was evaluated with SCORing Atopic Dermatitis (SCORAD). Data were analyzed by analysis of variance (ANOVA) and Kruskal-Wallis tests. Results: SCORAD was reduced after 60 days in groups D, E and DE by 34.8%, 35.7% and 64.3%, respectively (p = 0.004). Objective SCORAD also showed significant improvement. There was a positive correlation between SCORAD and intensity, objective, subjective and extent (p < 0.001). We found a significant negative association between plasma α-tocopherol and SCORAD, intensity, objective and extent (p = 0.02). Conclusion: This study supports the contributing and beneficial effects of vitamins D and E in the treatment of atopic dermatitis.
Editor: Oslo: Informa Healthcare USA on behalf of Informa UK Ltd
Idioma: Inglês

Links

Voltar para lista de resultados

Realização: Logos de Redes Sociais:

Randomized controlled trial using vitamins E and D supplementation in atopic dermatitis

Javanbakht, Mohammad Hassan ; Keshavarz, Seyed Ali ; Djalali, Mahmoud ; Siassi, Fereydoun ; Eshraghian, Mohammad Reza ; Firooz, Alireza ; Seirafi, Hassan ; Ehsani, Amir Hooshang ; Chamari, Maryam ; Mirshafiey, Abbas

Oslo: Informa Healthcare USA on behalf of Informa UK Ltd

Buscando em bases de dados remotas. Favor aguardar.