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Associates of bone mineral density in older African Americans

ROBBINS, John ; HIRSCH, Calvin ; CAULEY, Jane

Journal of the National Medical Association, 2004-12, Vol.96 (12), p.1609-1615 [Periódico revisado por pares]

Thorofare, NJ: Slack

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  • Título:
    Associates of bone mineral density in older African Americans
  • Autor: ROBBINS, John ; HIRSCH, Calvin ; CAULEY, Jane
  • Assuntos: Aged ; Biological and medical sciences ; Body Weight ; Bone Density ; Cross-Sectional Studies ; Diseases of the osteoarticular system ; Female ; General aspects ; Humans ; Male ; Medical sciences ; Osteoporosis - ethnology ; Osteoporosis. Osteomalacia. Paget disease ; Risk Factors
  • É parte de: Journal of the National Medical Association, 2004-12, Vol.96 (12), p.1609-1615
  • Notas: ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-2
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  • Descrição: To assess correlates of bone mineral density (BMD) in older African Americans. 189 women and 115 men over age 64. Variables investigated: BMD by dual X-ray absorptiometry (DXA), medications, cardiovascular disease risk factors, demographic, lifestyle factors and functional status. Variables showing univariate correlation with BMD (p < or = 0.1) were entered into sex-stratified linear regression models. Age range 67-96 (mean 75). The mean BMD (gm/ cm2 +/- standard deviation) is reported for three sites. Total body: 1.03 (+/- 0.12) in women, 1.21 (+/- 0.11) in men. Spine: 1.05 (+/- 0.24) in women, 1.22 (+/- 0.26) in men. Total hip: 0.85 (+/- 0.15) in women, 1.04 (+/- 0.17) in men. Gender was significantly associated with BMD (t-test, p < 0.001). The R2 for tested variables were highly significant only for weight. Age was only significant for total hip in women (p < 0.05). Each kilogram of weight change was associated with a 5.3-6.8 mg/cm2 change in BMD. In a population-based cohort of older African Americans, average BMD was significantly greater in men than women. Weight accounted for most of the explained variability (R2) in BMD; age added little to the overall R2. Lower-weight, older African-American men and women are at significantly increased risk for low BMD and, thus, likely to be at greater risk for osteoporotic fracture.
  • Editor: Thorofare, NJ: Slack
  • Idioma: Inglês
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