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정상월경주기 및 남성화 호르몬 기능이상자에서의 방사면역측정법을 이용한 혈청 Testosterone

최성기 ; SK Choi ; 김윤호 ; YH Kim ; 나종구 ; Rha CG ; 정병래 ; BL Chung

Obstetrics & gynecology science, 1975-06, Vol.18 (6), p.395 [Periódico revisado por pares]

대한산부인과학회

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  • Título:
    정상월경주기 및 남성화 호르몬 기능이상자에서의 방사면역측정법을 이용한 혈청 Testosterone
  • Autor: 최성기 ; SK Choi ; 김윤호 ; YH Kim ; 나종구 ; Rha CG ; 정병래 ; BL Chung
  • É parte de: Obstetrics & gynecology science, 1975-06, Vol.18 (6), p.395
  • Notas: The Korean Association of Obstetricians and Gynecologists
  • Descrição: In this study serum testosterone levels of 4 normal women through full menstrual cycle , 4 female patients with various androgenic disorders and a healthy adult man were measured by modified Midgley method of double antibody technique using radioimmunoassay kit obtained from Serono Immunochemical Company. The results were as follows; 1. The recovery of testosterone after extraction with ethanol was 89.2%. However, ethanol and benzene was improper as extractive solvent because of difficulty in its separation and evaporation. The recoveries of testosterone with ether, petroleum ether and benzene were 68.9%, 15.6% and 67.7% respectively thus it was found that ethyl ether is most suitable for extraction of testosterone. 2. The mean serum testosterone level after extraction of female patients with androgenic disorders was 2.06+-1.09 ng/ml, while that without extraction was above 4 ng/ml. The difference in testosterone value between before and after extraction was sighnificantly 3. The mean serum testosterone level through menstrual cycle in normal women was 1.27 ng/ml. The average serum testosterone levels in menstrual phase and premenstrual phase were 0.97 ng/ml and 1.06 ng/ml, respectively. On the other hand, the level in ovulatory phase was 1.96 ng/ml, which is sighnificantly higher than those in menstrual and premenstrual phase.
  • Editor: 대한산부인과학회
  • Idioma: Coreano
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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