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The challenge of enzyme cost in the production of lignocellulosic biofuels

Klein-Marcuschamer, Daniel ; Oleskowicz-Popiel, Piotr ; Simmons, Blake A. ; Blanch, Harvey W.

Biotechnology and bioengineering, 2012-04, Vol.109 (4), p.1083-1087 [Periódico revisado por pares]

Hoboken: Wiley Subscription Services, Inc., A Wiley Company

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Título:
The challenge of enzyme cost in the production of lignocellulosic biofuels
Autor: Klein-Marcuschamer, Daniel ; Oleskowicz-Popiel, Piotr ; Simmons, Blake A. ; Blanch, Harvey W.
Assuntos: Batch Cell Culture Techniques - economics ; Benchmarking ; Biodiesel fuels ; biofuels ; Biofuels - economics ; Capital Expenditures ; Carbohydrates ; cellulase ; Cellulase - economics ; Cost analysis ; Costs and Cost Analysis ; enzyme costs ; enzyme loading ; Enzymes ; Ethanol ; Ethanol - economics ; Ethanol - metabolism ; Ethyl alcohol ; Fermentation ; Fuels ; Fungal Proteins - economics ; Glycine max - economics ; Lignin - economics ; Lignin - metabolism ; Lignocellulose ; Models, Economic ; Populus ; process model ; Raw materials ; Sensitivity analysis ; techno-economic analysis ; Trichoderma - enzymology ; Wood - economics ; Zea mays - economics
É parte de: Biotechnology and bioengineering, 2012-04, Vol.109 (4), p.1083-1087
Notas: ark:/67375/WNG-444X6BDL-L
ArticleID:BIT24370
istex:07CF123B7324387C53F3557D56F4D0A5CE8EC853
ObjectType-Article-1
SourceType-Scholarly Journals-1
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USDOE Office of Science (SC), Biological and Environmental Research (BER)
Descrição: With the aim of understanding the contribution of enzymes to the cost of lignocellulosic biofuels, we constructed a techno‐economic model for the production of fungal cellulases. We found that the cost of producing enzymes was much higher than that commonly assumed in the literature. For example, the cost contribution of enzymes to ethanol produced by the conversion of corn stover was found to be $0.68/gal if the sugars in the biomass could be converted at maximum theoretical yields, and $1.47/gal if the yields were based on saccharification and fermentation yields that have been previously reported in the scientific literature. We performed a sensitivity analysis to study the effect of feedstock prices and fermentation times on the cost contribution of enzymes to ethanol price. We conclude that a significant effort is still required to lower the contribution of enzymes to biofuel production costs. Biotechnol. Bioeng. 2012; 109:1083–1087. © 2011 Wiley Periodicals, Inc. The cost contribution of enzymes to the production of lignocellulosic biofuels has been widely debated. By modeling the production of cellulolytic enzymes and analyzing the technical and economic performance of the process, the authors estimated their cost. Furthermore, using information about enzyme use in typical biorefinery processes, the authors were able to determine the contribution of enzymes to the total cost of production of lignocellulosic ethanol. The authors concluded that this contribution is much higher than estimates given in the literature.
Editor: Hoboken: Wiley Subscription Services, Inc., A Wiley Company
Idioma: Inglês

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The challenge of enzyme cost in the production of lignocellulosic biofuels

Klein-Marcuschamer, Daniel ; Oleskowicz-Popiel, Piotr ; Simmons, Blake A. ; Blanch, Harvey W.

Hoboken: Wiley Subscription Services, Inc., A Wiley Company

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