Idioma:

Underwater versus conventional endoscopic mucosal resection for small size non-pedunculated colorectal polyps: a randomized controlled trial : (UEMR vs. CEMR for small size non-pedunculated colorectal polyps)

Zhang, Zhixin ; Xia, Yonghong ; Cui, Hongyao ; Yuan, Xin ; Wang, Chunnian ; Xie, Jiarong ; Tong, Yarong ; Wang, Weihong ; Xu, Lei

BMC gastroenterology, 2020-09, Vol.20 (1), p.311-311 [Periódico revisado por pares]

England: BioMed Central Ltd

Texto completo disponível

Citações Citado por

Enviar para

Título:
Underwater versus conventional endoscopic mucosal resection for small size non-pedunculated colorectal polyps: a randomized controlled trial : (UEMR vs. CEMR for small size non-pedunculated colorectal polyps)
Autor: Zhang, Zhixin ; Xia, Yonghong ; Cui, Hongyao ; Yuan, Xin ; Wang, Chunnian ; Xie, Jiarong ; Tong, Yarong ; Wang, Weihong ; Xu, Lei
Assuntos: Biopsy ; Care and treatment ; Clinical trials ; Colon ; Colonic polyps ; Colonic Polyps - pathology ; Colonic Polyps - surgery ; Colonoscopy ; Colorectal cancer ; Colorectal Neoplasms - pathology ; Comparative analysis ; Confidence intervals ; Conventional endoscopic mucosal resection ; Endoscopic Mucosal Resection - adverse effects ; Endoscopy ; Gastrointestinal endoscopy ; Hospitals ; Humans ; Intestinal Mucosa - pathology ; Intestinal Polyps - pathology ; Methods ; Mucosa ; Patients ; Polyps ; Statistical analysis ; Testing ; Tumors ; Underwater endoscopic mucosal resection
É parte de: BMC gastroenterology, 2020-09, Vol.20 (1), p.311-311
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-News-2
ObjectType-Feature-3
content type line 23
Descrição: Underwater endoscopic mucosal resection (UEMR) is a recently developed technique and can be performed during water-aided or ordinary colonoscopy for the treatment of colorectal polyps. The objective of this clinical trial was to evaluate the efficacy and safety of UEMR in comparison with conventional endoscopic mucosal resection (CEMR) of small non-pedunculated colorectal polyps. Patients with small size, non-pedunculated colorectal polyps (4-9 mm in size) who underwent colonoscopic polypectomy were enrolled in this multicenter randomized controlled clinical trial. The patients were randomly allocated to two groups, an UEMR group and a CEMR group. Efficacy and safety were compared between groups. In the intention-to-treat (ITT) analysis, the complete resection rate was 83.1% (59/71) in the UEMR group and 87.3% (62/71) in the CEMR group. The en-bloc resection rate was 94.4% (67/71) in the UEMR group and 91.5% (65/71) in the CEMR group (difference 2.9%; 90% CI - 4.2 to 9.9%), showed noninferiority (noninferiority margin - 5.7% < - 4.2%). No significant difference in procedure time (81 s vs. 72 s, P = 0.183) was observed. Early bleeding was observed in 1.4% of patients in the CEMR group (1/71) and 1.4% of patients in the UEMR group (1/71). None of the patients in the UEMR group complained of postprocedural bloody stool, whereas two patients in the CEMR group (2/64) reported this adverse event. Our results indicate that UEMR is safer and just as effective as CEMR in En-bloc resection for the treatment of small colorectal polyps as such, UEMR is recommended as an alternative approach to excising small and non-pedunculated colorectal adenomatous polyps. Clinical Trials.gov, NCT03833492 . Retrospectively registered on February 7, 2019.
Editor: England: BioMed Central Ltd
Idioma: Inglês

Links

View this record in MEDLINE/PubMed

Voltar para lista de resultados

Realização: Logos de Redes Sociais:

Underwater versus conventional endoscopic mucosal resection for small size non-pedunculated colorectal polyps: a randomized controlled trial : (UEMR vs. CEMR for small size non-pedunculated colorectal polyps)

Zhang, Zhixin ; Xia, Yonghong ; Cui, Hongyao ; Yuan, Xin ; Wang, Chunnian ; Xie, Jiarong ; Tong, Yarong ; Wang, Weihong ; Xu, Lei

England: BioMed Central Ltd

Buscando em bases de dados remotas. Favor aguardar.