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1,1-Disubstituted Tetrahydroisoquinolines from Enaminones via Pictet-Spengler Reaction

Venkov, Atanas P. ; Angelov, Plamen A.

Synthetic communications, 2003-09, Vol.33 (17), p.3025-3033 [Periódico revisado por pares]

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Título:
1,1-Disubstituted Tetrahydroisoquinolines from Enaminones via Pictet-Spengler Reaction
Autor: Venkov, Atanas P. ; Angelov, Plamen A.
Assuntos: Cyclization ; Enaminones ; Pictet-Spengler reaction ; Tetrahydroisoquinolines
É parte de: Synthetic communications, 2003-09, Vol.33 (17), p.3025-3033
Descrição: Enaminones, prepared by condensation of homoveratrylamine with 1,3-dicarbonyl compounds, undergo intramolecular cyclization in acidic media to afford 1,1-disubstituted tetrahydroisoquinolines in good yields. Further modification of the title compounds is demonstrated.
Editor: Taylor & Francis Group
Idioma: Inglês

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