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Population trends and variation in body mass index from 1971 to 2008 in the Framingham Heart Study Offspring Cohort

Block, Jason P ; Subramanian, S V ; Christakis, Nicholas A ; O'Malley, A James Zhang, Harry

PloS one, 2013-05, Vol.8 (5), p.e63217-e63217 [Periódico revisado por pares]

United States: Public Library of Science

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Título:
Population trends and variation in body mass index from 1971 to 2008 in the Framingham Heart Study Offspring Cohort
Autor: Block, Jason P ; Subramanian, S V ; Christakis, Nicholas A ; O'Malley, A James
Zhang, Harry
Assuntos: Adult ; Adults ; Aged ; Alcohol ; Biology ; Body mass ; Body Mass Index ; Body size ; Censuses ; Cohort Studies ; Demographics ; Demography ; Divergence ; Epidemics ; Female ; Health care policy ; Heart ; History, 20th Century ; History, 21st Century ; Humans ; Male ; Medical schools ; Medicine ; Men ; Middle Aged ; Neighborhoods ; Obesity ; Obesity - epidemiology ; Obesity - history ; Offspring ; Population ; Population Surveillance ; Poverty ; Progeny ; Risk Factors ; Sex ; Social and Behavioral Sciences ; Socioeconomic factors ; Standard deviation ; Studies ; Trends ; United States - epidemiology ; Variance ; Variation
É parte de: PloS one, 2013-05, Vol.8 (5), p.e63217-e63217
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Conceived and designed the experiments: JPB SVS NAC AJO. Analyzed the data: JPB SVS AJO. Wrote the paper: JPB SVS NAC AJO.
Competing Interests: The authors have declared that no competing interests exist.
Descrição: We examined body mass index (BMI) across place and time to determine the pattern of BMI mean and standard deviation trajectories. We included participants in the Framingham Heart Study (FHS) Offspring Cohort over eight waves of follow-up, from 1971 to 2008. After exclusions, the final sample size was 4569 subjects with 28,625 observations. We used multi-level models to examine population means and variation at the individual and neighborhood (census tracts) levels across time with measured BMI as the outcome, controlling for individual demographics and behaviors and neighborhood poverty. Because neighborhoods accounted for limited BMI variance, we removed this level as a source of variation in final models. We examined sex-stratified models with all subjects and models stratified by sex and baseline weight classification. Mean BMI increased from 24.0 kg/m(2) at Wave 1 to 27.7 at Wave 8 for women and from 26.6 kg/m(2) to 29.0 for men. In final models, BMI variation also increased from Waves 1 to 8, with the standard deviation increasing from 4.18 kg/m(2) to 6.15 for women and 3.31 kg/m(2) to 4.73 for men. BMI means increased in parallel across most baseline BMI weight classifications, except for more rapid increases through middle-age for obese women followed by declines in the last wave. BMI standard deviations also increased in parallel across baseline BMI classifications for women, with greater divergence of BMI variance for obese men compared to other weight classifications. Over nearly 40 years, BMI mean and variation increased in parallel across most baseline weight classifications in our sample. Individual-level characteristics, especially baseline BMI, were the primary factors in rising BMI. These findings have important implications not only for understanding the sources of the obesity epidemic in the United States but also for the targeting of interventions to address the epidemic.
Editor: United States: Public Library of Science
Idioma: Inglês

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Population trends and variation in body mass index from 1971 to 2008 in the Framingham Heart Study Offspring Cohort

Block, Jason P ; Subramanian, S V ; Christakis, Nicholas A ; O'Malley, A James Zhang, Harry

United States: Public Library of Science

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