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Hepcidin in the diagnosis of iron disorders

Girelli, Domenico ; Nemeth, Elizabeta ; Swinkels, Dorine W.

Blood, 2016-06, Vol.127 (23), p.2809-2813 [Periódico revisado por pares]

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Título:
Hepcidin in the diagnosis of iron disorders
Autor: Girelli, Domenico ; Nemeth, Elizabeta ; Swinkels, Dorine W.
Assuntos: Animals ; Biomarkers - blood ; Blood Chemical Analysis - methods ; Diagnostic Techniques and Procedures ; Hematologic Tests ; Hepcidins - blood ; Hepcidins - chemistry ; Hepcidins - physiology ; Humans ; Iron Metabolism Disorders - blood ; Iron Metabolism Disorders - diagnosis ; Iron Metabolism Disorders - therapy ; Spotlight
É parte de: Blood, 2016-06, Vol.127 (23), p.2809-2813
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
Descrição: The discovery of the iron-regulatory hormone hepcidin in 2001 has revolutionized our understanding of iron disorders, and its measurement should advance diagnosis/treatment of these conditions. Although several assays have been developed, a gold standard is still lacking, and efforts toward harmonization are ongoing. Nevertheless, promising applications can already be glimpsed, ranging from the use of hepcidin levels for diagnosing iron-refractory iron deficiency anemia to global health applications such as guiding safe iron supplementation in developing countries with high infection burden.
Editor: United States: Elsevier Inc
Idioma: Inglês

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