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Orbital angiolymphoid hyperplasia with eosinophilia. Presentation as chalazion

Archer, K F ; Hurwitz, J J ; Heathcote, G

Ophthalmic plastic and reconstructive surgery, 1991, Vol.7 (3), p.208-221 [Periódico revisado por pares]

United States

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  • Título:
    Orbital angiolymphoid hyperplasia with eosinophilia. Presentation as chalazion
  • Autor: Archer, K F ; Hurwitz, J J ; Heathcote, G
  • Assuntos: Angiolymphoid Hyperplasia with Eosinophilia - diagnostic imaging ; Angiolymphoid Hyperplasia with Eosinophilia - pathology ; Angiolymphoid Hyperplasia with Eosinophilia - surgery ; Chalazion - diagnosis ; Diagnosis, Differential ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Orbital Diseases - diagnostic imaging ; Orbital Diseases - pathology ; Orbital Diseases - surgery ; Tomography, X-Ray Computed
  • É parte de: Ophthalmic plastic and reconstructive surgery, 1991, Vol.7 (3), p.208-221
  • Notas: ObjectType-Case Study-3
    SourceType-Scholarly Journals-1
    content type line 23
    ObjectType-Review-1
    ObjectType-Feature-5
    ObjectType-Report-2
    ObjectType-Article-4
  • Descrição: Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon, benign slow-growing lesion primarily found in the head and neck region, with onset between the third and fourth decades, and a female predominance in the nonOriental population. Kimura's disease, occurring primarily in young Oriental males, is a similar lesion with peripheral blood eosinophilia, regional lymphadenopathy, and occasional nephrotic syndrome. Orbital ALHE is rare, previously reported in only nine patients. Orbital ALHE is a solitary lesion, with an older age of onset, between the fourth and eighth decades, than ALHE elsewhere. There is a male predominance, in contradistinction to ALHE elsewhere in nonOrientals. Orbital ALHE demonstrates the same histology as other locations, with exuberant capillary proliferation and an inflammatory infiltrate of eosinophils, lymphocytes, plasma cells, and mast cells. The maturity of the lesion, not necessarily the duration, determines the presence of lymphoid follicles and germinal centers. A distinctive endothelial cell lines and even extends into the vascular lumens. Peripheral blood eosinophilia occasionally occurs, and a few cases have been reported in conjunction with asthma. Therapeutic regimens for ALHE include excision, carbon dioxide and argon laser, irradiation, steroids, electrodesiccation, and cytotoxic agents. Orbital lesions have been treated successfully with excision, or biopsy with debulking, or steroids.
  • Editor: United States
  • Idioma: Inglês

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