Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

Pardiñas, Antonio F ; Holmans, Peter ; Pocklington, Andrew J ; Escott-Price, Valentina ; Ripke, Stephan ; Carrera, Noa ; Legge, Sophie E ; Bishop, Sophie ; Cameron, Darren ; Hamshere, Marian L ; Han, Jun ; Hubbard, Leon ; Lynham, Amy ; Mantripragada, Kiran ; Rees, Elliott ; MacCabe, James H ; McCarroll, Steven A ; Baune, Bernhard T ; Breen, Gerome ; Byrne, Enda M ; Dannlowski, Udo ; Eley, Thalia C ; Hayward, Caroline ; Martin, Nicholas G ; McIntosh, Andrew M ; Plomin, Robert ; Porteous, David J ; Wray, Naomi R ; Caballero, Armando ; Geschwind, Daniel H ; Huckins, Laura M ; Ruderfer, Douglas M ; Santiago, Enrique ; Sklar, Pamela ; Stahl, Eli A ; Won, Hyejung ; Agerbo, Esben ; Als, Thomas D ; Andreassen, Ole A ; Bækvad-Hansen, Marie ; Mortensen, Preben Bo ; Pedersen, Carsten Bøcker ; Børglum, Anders D ; Bybjerg-Grauholm, Jonas ; Djurovic, Srdjan ; Durmishi, Naser ; Pedersen, Marianne Giørtz ; Golimbet, Vera ; Grove, Jakob ; Hougaard, David M ; Mattheisen, Manuel ; Molden, Espen ; Mors, Ole ; Nordentoft, Merete ; Pejovic-Milovancevic, Milica ; Sigurdsson, Engilbert ; Silagadze, Teimuraz ; Hansen, Christine Søholm ; Stefansson, Kari ; Stefansson, Hreinn ; Steinberg, Stacy ; Tosato, Sarah ; Werge, Thomas ; Collier, David A ; Rujescu, Dan ; Kirov, George ; Owen, Michael J ; O'Donovan, Michael C ; Walters, James T R

Nature genetics, 2018-03, Vol.50 (3), p.381-389 [Periódico revisado por pares]

United States: Nature Publishing Group

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