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Prognostic factors in salvage surgery for recurrent oral and oropharyngeal cancer

Gonçalves Agra, Ivan Marcelo ; Lopes Carvalho, André ; Samsonovski Ulbrich, Fábio ; de Campos, Olímpio Daniel ; Martins, Everton Pontes ; Magrin, José ; Kowalski, Luiz Paulo

Head & neck, 2006-02, Vol.28 (2), p.107-113 [Periódico revisado por pares]

Hoboken: Wiley Subscription Services, Inc., A Wiley Company

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Título:
Prognostic factors in salvage surgery for recurrent oral and oropharyngeal cancer
Autor: Gonçalves Agra, Ivan Marcelo ; Lopes Carvalho, André ; Samsonovski Ulbrich, Fábio ; de Campos, Olímpio Daniel ; Martins, Everton Pontes ; Magrin, José ; Kowalski, Luiz Paulo
Assuntos: Adult ; Aged ; Biological and medical sciences ; Carcinoma, Squamous Cell - mortality ; Carcinoma, Squamous Cell - secondary ; Carcinoma, Squamous Cell - surgery ; Disease-Free Survival ; Female ; Head and Neck Neoplasms - mortality ; Head and Neck Neoplasms - secondary ; Head and Neck Neoplasms - surgery ; Humans ; Male ; Medical sciences ; Middle Aged ; Mouth Neoplasms - mortality ; Mouth Neoplasms - surgery ; Neoplasm Recurrence, Local - surgery ; oral cancer ; oropharyngeal cancer ; Oropharyngeal Neoplasms - mortality ; Oropharyngeal Neoplasms - surgery ; Otorhinolaryngology. Stomatology ; Prognosis ; prognostic factors ; recurrences ; Retrospective Studies ; salvage surgery ; Salvage Therapy ; Survival Rate ; Tumors ; Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
É parte de: Head & neck, 2006-02, Vol.28 (2), p.107-113
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Descrição: Background. Therapeutic decisions in recurrent oral and oropharyngeal squamous carcinoma (SCC) remain controversial. Methods. Two hundred forty‐six consecutive patients who underwent salvage surgery for recurrent squamous cell carcinoma (SCC) of the oral cavity and oropharynx were studied. The tumor sites were lip, 33 cases; oral cavity, 143; oropharynx, 70. The previous treatment was surgery in 73 patients, radiotherapy in 96, combined surgery and radiotherapy in 76, and chemotherapy in one. The clinical stage of recurrence was I/II in 51 cases and III/IV in 195 cases. The disease‐free interval (DFI) was less than 1 year in 156 cases and greater than 1 year in 90 cases. Results. The rate of recurrence was 54.9%, and the overall 5‐year actuarial survival rate was 32.3%. The significant prognostic factors in multivariate analysis were restage (p = .049) and DFI (p = .045). Conclusion. Patients with recurrent oral and oropharyngeal SCC at initial clinical stages (rCS I and II) and with a DFI greater than 1 year had a favorable prognosis. © 2005 Wiley Periodicals, Inc. Head Neck 27: XXX–XXX, 2005
Editor: Hoboken: Wiley Subscription Services, Inc., A Wiley Company
Idioma: Inglês

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Prognostic factors in salvage surgery for recurrent oral and oropharyngeal cancer

Gonçalves Agra, Ivan Marcelo ; Lopes Carvalho, André ; Samsonovski Ulbrich, Fábio ; de Campos, Olímpio Daniel ; Martins, Everton Pontes ; Magrin, José ; Kowalski, Luiz Paulo

Hoboken: Wiley Subscription Services, Inc., A Wiley Company

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