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Uterine cavity embryonal rhabdomyosarcoma

Sardinha, Marina Gomes Pereira; Ramajo, Fábio Morozetti; Ponce, Cesar Cilento; Marques, Camila Franzin; Bittencourt, Carolina Marques Fontes; Caldano, Fernando Gardin; Moço, José Matheus Frizzo Lopes; Yano, Otávio De Lacquila; Reis, Pedro Marques Da Rosa; Malaguti, Vinicius Silva; Sousa, Catarina Tealdi Reno Gandra De; Nogueira Junior, Roberto Cesar

Autopsy and Case Reports; Vol. 9 Núm. 3 (2019); e2019104

Universidade de São Paulo. Hospital Universitário 2019-07-23

Acesso online

  • Título:
    Uterine cavity embryonal rhabdomyosarcoma
  • Autor: Sardinha, Marina Gomes Pereira; Ramajo, Fábio Morozetti; Ponce, Cesar Cilento; Marques, Camila Franzin; Bittencourt, Carolina Marques Fontes; Caldano, Fernando Gardin; Moço, José Matheus Frizzo Lopes; Yano, Otávio De Lacquila; Reis, Pedro Marques Da Rosa; Malaguti, Vinicius Silva; Sousa, Catarina Tealdi Reno Gandra De; Nogueira Junior, Roberto Cesar
  • Assuntos: Rhabdomyosarcoma; Embryonal; Uterine Cervical Neoplasms; Cervix Uteri
  • É parte de: Autopsy and Case Reports; Vol. 9 Núm. 3 (2019); e2019104
  • Descrição: Rhabdomyosarcoma (RMS) is a rare solid tumor in childhood and adolescence. The higher incidence is predominant during the first two decades of life. According to the Intergroup RMS Study Group, the embryonal RMS (ERMS), botryoidal variant, constitutes a histological subtype characterized as a “grape-like” lesion of 2.0 cm to 9.5 cm. The treatment involves chemotherapy, surgery, and/or radiotherapy. We present the case of a 14-year-old female patient diagnosed with ERMS, botryoidal variant, which originated in the uterine cervix with vaginal externalization. The initial therapeutic approach comprised an initial prolapsed mass excision followed by Wertheim–Meigs surgery due to the tumor extension. No consensual protocol to ERMS treatment is found in the medical literature; however, a combined approach seems to offer a better result. The postoperative time period was uneventful and the patient followed an adjuvant therapy with vincristine, d-actinomycin, and cyclophosphamide. A comprehensive evaluation of the therapeutic options preserving the reproductive function—unfortunately not always possible—is part of a multi-disciplined care team concerning the pediatric patients.
  • Títulos relacionados: https://www.revistas.usp.br/autopsy/article/view/160210/154556; https://www.revistas.usp.br/autopsy/article/view/160210/154557
  • Editor: Universidade de São Paulo. Hospital Universitário
  • Data de criação/publicação: 2019-07-23
  • Formato: Adobe PDF
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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