skip to main content
Idioma:
Primo Search
Clear Search Box
Search in: Búsqueda General
Búsqueda Avanzada
Búsqueda por Índices

Extended criteria donor organ use for heart-lung transplantation in the modern era

Weingarten, Noah; Iyengar, Amit; Herbst, David Alan; Helmers, Mark; Meldrum, Danika; Guevara-Plunkett, Sara; Dominic, Jessica; Atluri, Pavan

Clinics; v. 78 (2023); 100205

Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo 2023-04-28

Acceso en línea

  • Título:
    Extended criteria donor organ use for heart-lung transplantation in the modern era
  • Autor: Weingarten, Noah; Iyengar, Amit; Herbst, David Alan; Helmers, Mark; Meldrum, Danika; Guevara-Plunkett, Sara; Dominic, Jessica; Atluri, Pavan
  • Materias: Organ Donor Management; Heart-Lung Transplantation; Heart Transplantation; Lung Transplantation
  • Es parte de: Clinics; v. 78 (2023); 100205
  • Descripción: Background: Demand for donor hearts and lungs exceeds their supply. Extended Criteria Donor (ECD) organs are used to help meet this demand, but their impact on heart-lung transplantation outcomes is poorly characterized. Methods and results: : The United Network for Organ Sharing was queried for data on adult heart-lung transplantation recipients (n = 447) from 2005‒2021. Recipients were stratified based on whether they received ECD hearts and/or lungs. Morbidity was analyzed using Kruskal-Wallis, chi-square, and Fisher's exact tests. Mortality was analyzed using Kaplan-Meier estimation, log-rank tests and Cox regression. Sixty-five (14.5%) patients received two ECD organs, 134 (30.0%) received only an ECD lung, and 65 (14.5%) only an ECD heart. Recipients of two ECD organs were older, more likely to have diabetes, and more likely transplanted from 2015‒2021 (p < 0.05). Groups did not differ by pre-transplant diagnosis, intensive care unit disposition, life support use, or hemodynamics. Group five-year survival rates ranged from 54.5% to 63.2% (p = 0.428). Groups did not differ by 30-day mortality, strokes, graft rejection, or hospital length of stay. Conclusions: Using ECD hearts and/or lungs for heart-lung transplantation is not associated with increased mortality and is a safe strategy for increasing donor organ supply in this complex patient population.
  • Títulos relacionados: https://www.revistas.usp.br/clinics/article/view/213779/195941
  • Editor: Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
  • Fecha de creación: 2023-04-28
  • Formato: Adobe PDF
  • Idioma: Inglés
Enlaces
Volver a la lista de resultados
Ir a la página anteriorAnterior Resultado  9 SiguienteIr a la siguiente página

  • Realización: ABCD-USP USP   Logos de Redes Sociales: Freepik

Buscando en bases de datos remotas, por favor espere

  • Buscando por
  • enscope:(USP_PRODUCAO),scope:(USP_EBOOKS),scope:("PRIMO"),scope:(USP),scope:(USP_EREVISTAS),scope:(USP_FISICO),primo_central_multiple_fe
  • Mostrar lo que tiene hasta ahora