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Short epitope-based synthetic peptides for serodiagnosis of human strongyloidiasis

Feliciano, Nágilla D ; Ribeiro, Vanessa S ; Gonzaga, Henrique T ; Santos, Fabiana A.A ; Fujimura, Patricia T ; Goulart, Luiz R ; Costa-Cruz, Julia M

Immunology letters, 2016-04, Vol.172, p.89-93 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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Título:
Short epitope-based synthetic peptides for serodiagnosis of human strongyloidiasis
Autor: Feliciano, Nágilla D ; Ribeiro, Vanessa S ; Gonzaga, Henrique T ; Santos, Fabiana A.A ; Fujimura, Patricia T ; Goulart, Luiz R ; Costa-Cruz, Julia M
Assuntos: Allergy and Immunology ; Animals ; Antibodies, Helminth - blood ; Biomarkers - metabolism ; Brazil ; Computer Simulation ; Cross Reactions ; Enzyme-Linked Immunosorbent Assay ; Epitope Mapping ; Epitopes, B-Lymphocyte - immunology ; Humans ; Immunodiagnosis ; Neglected Diseases - immunology ; Peptide Fragments - chemical synthesis ; Peptide Fragments - immunology ; Phage display ; Predictive Value of Tests ; Prognosis ; Sensitivity and Specificity ; Serologic Tests - methods ; Strongyloides stercoralis ; Strongyloides stercoralis - immunology ; Strongyloidiasis ; Strongyloidiasis - immunology ; Synthetic peptides
É parte de: Immunology letters, 2016-04, Vol.172, p.89-93
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Descrição: Highlights • Peptides (C10 and D3) were synthesized derived from phage displayed mimotope ligands. • Synthetic peptides were tested to diagnose strongyloidiasis in serum samples. • Conformational epitopes were predicted and aligned to known protein structures. • D3 had excellent performance with the highest diagnostic efficiency. • C10 and D3 may become potential biomarkers for strongyloidiasis serodiagnosis.
Editor: Netherlands: Elsevier B.V
Idioma: Inglês

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Short epitope-based synthetic peptides for serodiagnosis of human strongyloidiasis

Feliciano, Nágilla D ; Ribeiro, Vanessa S ; Gonzaga, Henrique T ; Santos, Fabiana A.A ; Fujimura, Patricia T ; Goulart, Luiz R ; Costa-Cruz, Julia M

Netherlands: Elsevier B.V

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