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Thermal balloon endometrial ablation: safety aspects evaluated by serosal temperature, light microscopy and electron microscopy

Andersen, Lars F ; Meinert, Lars ; Rygaard, Carsten ; Junge, Jette ; Prentø, Poul ; Ottesen, Bent S

European journal of obstetrics & gynecology and reproductive biology, 1998-07, Vol.79 (1), p.63-68 [Periódico revisado por pares]

Shannon: Elsevier Ireland Ltd

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Título:
Thermal balloon endometrial ablation: safety aspects evaluated by serosal temperature, light microscopy and electron microscopy
Autor: Andersen, Lars F ; Meinert, Lars ; Rygaard, Carsten ; Junge, Jette ; Prentø, Poul ; Ottesen, Bent S
Assuntos: Adult ; Biological and medical sciences ; Body Temperature Regulation - physiology ; Catheter Ablation - adverse effects ; Catheterization - adverse effects ; Chorion - physiology ; Endometrial ablation ; Evaluation Studies as Topic ; Female ; Genital system. Mammary gland ; Humans ; Hyperthermia, Induced ; Hysterectomy ; Medical sciences ; Menorrhagia ; Menorrhagia - surgery ; Menorrhagia - therapy ; Microscopy - methods ; Microscopy, Electron ; Middle Aged ; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) ; Thermal balloon
É parte de: European journal of obstetrics & gynecology and reproductive biology, 1998-07, Vol.79 (1), p.63-68
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
Descrição: Objectives: Thermal balloon endometrial ablation is a new method for treating menorrhagia. The technique appears to be less difficult compared to standard hysteroscopic ablation techniques and to be significantly safer. The influence into the uterine wall of the thermal balloon ablation procedure was investigated with special reference to the ability of total destruction of the endometrium and the thermal action on the myometrium and the serosa. Study design: Temperatures were measured at the uterine serosal surface during thermal balloon endometrial ablation for 8–16 min in eight patients. After subsequent hysterectomy the extent of thermal damage into the myometrium was assessed by light and electron microscopy. Results: The highest temperature measured on the uterine serosa was 39.1°C. Coagulation of the myometrium adjacent to the endometrium could be demonstrated by light microscopy in all patients, with a maximum depth of 11.5 mm. By electron microscopy no influence of heat could be demonstrated beyond 15 mm from the endometrial surface. Conclusion: Up to 16 min of thermal balloon endometrial ablation therapy can destroy the endometrium and the submucosal layers. The myometrium is only coagulated to a depth where full thickness necrosis or injury is unlikely.
Editor: Shannon: Elsevier Ireland Ltd
Idioma: Inglês

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Thermal balloon endometrial ablation: safety aspects evaluated by serosal temperature, light microscopy and electron microscopy

Andersen, Lars F ; Meinert, Lars ; Rygaard, Carsten ; Junge, Jette ; Prentø, Poul ; Ottesen, Bent S

Shannon: Elsevier Ireland Ltd

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