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Secondary syphilis presenting as a corymbiform syphilide: case report and review

Eyer-Silva, Walter de Araujo ; Souza, Viviane Primo Basílio de ; Silva, Guilherme Almeida Rosa da ; Brasil, Fernando Vieira ; Portela, Alessandra Dos Santos ; Carvalho, Ricardo de Souza ; Neves-Motta, Rogerio ; Martins, Carlos José

Revista do Instituto de Medicina Tropical de São Paulo, 2018-08, Vol.60, p.e40 [Periódico revisado por pares]

Brazil: Instituto de Medicina Tropical

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  • Título:
    Secondary syphilis presenting as a corymbiform syphilide: case report and review
  • Autor: Eyer-Silva, Walter de Araujo ; Souza, Viviane Primo Basílio de ; Silva, Guilherme Almeida Rosa da ; Brasil, Fernando Vieira ; Portela, Alessandra Dos Santos ; Carvalho, Ricardo de Souza ; Neves-Motta, Rogerio ; Martins, Carlos José
  • Assuntos: Case Report ; Corymbiform ; Corymbose ; HIV infection ; Syphilis ; TROPICAL MEDICINE
  • É parte de: Revista do Instituto de Medicina Tropical de São Paulo, 2018-08, Vol.60, p.e40
  • Notas: The authors declare there is no conflict of interest.
    Informed consent of the patient was obtained for publication of the case.
    The first two authors contributed equally to the study
    CONFLICT OF INTERESTS
    INFORMED CONSENT
    AUTHORS’ CONTRIBUTIONS
    WAES, VPB, and CJM proposed the publication of the case. WAES and VPB drafted the manuscript. WAES, VPB, GARS, FVB, ASP, DJHPS, RSC, RNM, and CJM took part in the clinical management of the patient. All authors revised the literature and provided important contributions to conception, design, acquisition of data, analysis, interpretation, and intellectual contributions to the final version.
  • Descrição: It is essential that healthcare providers are familiar with the full spectrum of clinical presentations of syphilis. A rare manifestation of secondary syphilis is the corymbiform (or corymbose) arrangement, in which a central greater papule is surrounded by smaller satellite lesions. Very few reports of corymbiform syphilis are available in current biomedical databases. We present the case of a 28 year-old HIV-infected male patient on regular, successful antiretroviral therapy who developed an asymptomatic corymbiform maculopapular lesion in the medial aspect of the right thigh. There were also a few brownish macular lesions on the left sole. New serological tests for syphilis (which had been negative in the past) were reactive. The coymbiform lesion slowly regressed and the non-treponemal test reverted to negative after benzathine penicillin G treatment. A review of the literature is provided. This is the first report of corymbiform syphilis in an HIV-infected patient.
  • Editor: Brazil: Instituto de Medicina Tropical
  • Idioma: Inglês;Português
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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