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Primary immunodeficiencies: 2009 update

Notarangelo, Luigi D., MD ; Fischer, Alain, MD ; Geha, Raif S., MD ; Casanova, Jean-Laurent, MD ; Chapel, Helen, MD ; Conley, Mary Ellen, MD ; Cunningham-Rundles, Charlotte, MD, PhD ; Etzioni, Amos, MD ; Hammartröm, Lennart, MD ; Nonoyama, Shigeaki, MD ; Ochs, Hans D., MD ; Puck, Jennifer, MD ; Roifman, Chaim, MD ; Seger, Reinhard, MD ; Wedgwood, Josiah, MD, PhD

Journal of allergy and clinical immunology, 2009-12, Vol.124 (6), p.1161-1178 [Periódico revisado por pares]

New York, NY: Mosby, Inc

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Título:
Primary immunodeficiencies: 2009 update
Autor: Notarangelo, Luigi D., MD ; Fischer, Alain, MD ; Geha, Raif S., MD ; Casanova, Jean-Laurent, MD ; Chapel, Helen, MD ; Conley, Mary Ellen, MD ; Cunningham-Rundles, Charlotte, MD, PhD ; Etzioni, Amos, MD ; Hammartröm, Lennart, MD ; Nonoyama, Shigeaki, MD ; Ochs, Hans D., MD ; Puck, Jennifer, MD ; Roifman, Chaim, MD ; Seger, Reinhard, MD ; Wedgwood, Josiah, MD, PhD
Assuntos: Allergy and Immunology ; Autoimmunity - immunology ; autoinflammatory disorders ; B cells ; B-Lymphocytes - immunology ; B-Lymphocytes - metabolism ; Bacterial infections ; Biological and medical sciences ; Classification ; complement ; Complement System Proteins - immunology ; Complement System Proteins - metabolism ; Cytokines ; Cytokines - immunology ; Cytokines - metabolism ; Defects ; Deoxyribonucleic acid ; DNA ; DNA repair defects ; Fundamental and applied biological sciences. Psychology ; Fundamental immunology ; Genes ; Genotype & phenotype ; Humans ; immune dysregulation syndromes ; Immunity, Innate ; Immunoglobulins - blood ; Immunologic Deficiency Syndromes - classification ; Immunologic Deficiency Syndromes - immunology ; Immunologic Deficiency Syndromes - therapy ; Immunopathology ; innate immunity ; Killer Cells, Natural - immunology ; Killer Cells, Natural - metabolism ; Kinases ; Medical sciences ; Medicin och hälsovetenskap ; Meetings ; Mutation ; phagocytes ; predominantly antibody deficiencies ; Primary immunodeficiencies ; Proteins ; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis ; severe combined immunodeficiency ; T cells ; T-Lymphocytes - immunology ; T-Lymphocytes - metabolism ; Viral infections
É parte de: Journal of allergy and clinical immunology, 2009-12, Vol.124 (6), p.1161-1178
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Descrição: More than 50 years after Ogdeon Bruton's discovery of congenital agammaglobulinemia, human primary immunodeficiencies (PIDs) continue to unravel novel molecular and cellular mechanisms that govern development and function of the human immune system. This report provides the updated classification of PIDs that has been compiled by the International Union of Immunological Societies Expert Committee on Primary Immunodeficiencies after its biannual meeting in Dublin, Ireland, in June 2009. Since the appearance of the last classification in 2007, novel forms of PID have been discovered, and additional pathophysiology mechanisms that account for PID in human beings have been unraveled. Careful analysis and prompt recognition of these disorders is essential to prompt effective forms of treatment and thus to improve survival and quality of life in patients affected with PIDs.
Editor: New York, NY: Mosby, Inc
Idioma: Inglês

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Primary immunodeficiencies: 2009 update

New York, NY: Mosby, Inc

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