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Differentiated thyroid carcinomas: treatment of distant metastases. [Long term study of sodium iodine-131 effect after surgery]
Harness, J.K. ; Thompson, N.W. ; Sisson, J.C. ; Beierwaltes, W.H.
Arch. Surg. (Chicago); (United States), 1974, Vol.108
United States
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Título:
Differentiated thyroid carcinomas: treatment of distant metastases. [Long term study of sodium iodine-131 effect after surgery]
Autor:
Harness, J.K.
;
Thompson, N.W.
;
Sisson, J.C.
;
Beierwaltes, W.H.
Assuntos:
560161 -- Radionuclide Effects, Kinetics, & Toxicology-- Man
;
ALKALI METAL COMPOUNDS
;
BETA DECAY RADIOISOTOPES
;
BETA-MINUS DECAY RADIOISOTOPES
;
BIOLOGICAL EFFECTS
;
BIOLOGICAL RADIATION EFFECTS
;
BODY
;
CARCINOMAS
;
DAYS LIVING RADIOISOTOPES
;
DISEASES
;
DRUGS
;
ENDOCRINE GLANDS
;
GLANDS
;
HALIDES
;
HALOGEN COMPOUNDS
;
INORGANIC PHOSPHORS
;
INTERMEDIATE MASS NUCLEI
;
IODIDES
;
IODINE 131
;
IODINE COMPOUNDS
;
IODINE ISOTOPES
;
ISOTOPES
;
LABELLED COMPOUNDS
;
MEDICINE
;
METASTASES
;
NEOPLASMS
;
NUCLEAR MEDICINE
;
NUCLEI
;
ODD-EVEN NUCLEI
;
ORGANS
;
PHOSPHORS
;
RADIATION EFFECTS
;
RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT
;
RADIOACTIVE MATERIALS
;
RADIOISOTOPES
;
RADIOLOGY
;
RADIOLOGY AND NUCLEAR MEDICINE
;
RADIOPHARMACEUTICALS
;
RADIOTHERAPY
;
SODIUM COMPOUNDS
;
SODIUM IODIDES
;
SURGERY
;
THERAPY 550600 -- Medicine
;
THYROID
;
THYROIDECTOMY
É parte de:
Arch. Surg. (Chicago); (United States), 1974, Vol.108
Notas:
None
Descrição:
During the 26-year period from 1947 to 1973, 333 patients with differentiated thyroid carcinomas were treated with sodium iodide I 131 post-operatively. Thirty-six of these (10.6 percent) had metastases to lung or bone or both. The mean age at the time of diagnosis was 36.1 years (range, 6 to 69 years). Mortality from thyroid carcinomas was 27.8 percent. Average follow-up interval from diagnosis was 19.8 years for those with papillary carinomas and lung metastases and 23.0 years for those with follicular carcinomas and lung metastases. Although seven of ten patients with bone metastases died, the five-year survival was 100 percent in this group. The average dose of sodium iodide I 131 was 383.2 millicuries for papillary distant metastases and 571.2 millicuries for follicular metastases. Total thyroidectomy prior to treatment of distant metastases with sodium iodide I 131 is important for successful management.
Editor:
United States
Idioma:
Inglês
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