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Photodynamic inactivation of mammalian viruses and bacteriophages

Costa, Liliana ; Faustino, Maria Amparo F ; Neves, Maria Graça P M S ; Cunha, Angela ; Almeida, Adelaide

Viruses, 2012-07, Vol.4 (7), p.1034-1074 [Periódico revisado por pares]

Switzerland: MDPI AG

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Título:
Photodynamic inactivation of mammalian viruses and bacteriophages
Autor: Costa, Liliana ; Faustino, Maria Amparo F ; Neves, Maria Graça P M S ; Cunha, Angela ; Almeida, Adelaide
Assuntos: Animals ; bacteriophages ; Bacteriophages - drug effects ; Bacteriophages - physiology ; Bacteriophages - radiation effects ; Humans ; mammalian viruses ; Photochemotherapy ; photodynamic therapy ; photosensitizer ; Photosensitizing Agents - toxicity ; Review ; viral photoinactivation process ; Virus Diseases - drug therapy ; Virus Diseases - virology ; Virus Inactivation - drug effects ; Virus Inactivation - radiation effects ; Viruses - drug effects ; Viruses - radiation effects
É parte de: Viruses, 2012-07, Vol.4 (7), p.1034-1074
Descrição: Photodynamic inactivation (PDI) has been used to inactivate microorganisms through the use of photosensitizers. The inactivation of mammalian viruses and bacteriophages by photosensitization has been applied with success since the first decades of the last century. Due to the fact that mammalian viruses are known to pose a threat to public health and that bacteriophages are frequently used as models of mammalian viruses, it is important to know and understand the mechanisms and photodynamic procedures involved in their photoinactivation. The aim of this review is to (i) summarize the main approaches developed until now for the photodynamic inactivation of bacteriophages and mammalian viruses and, (ii) discuss and compare the present state of the art of mammalian viruses PDI with phage photoinactivation, with special focus on the most relevant mechanisms, molecular targets and factors affecting the viral inactivation process.
Editor: Switzerland: MDPI AG
Idioma: Inglês

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Photodynamic inactivation of mammalian viruses and bacteriophages

Costa, Liliana ; Faustino, Maria Amparo F ; Neves, Maria Graça P M S ; Cunha, Angela ; Almeida, Adelaide

Switzerland: MDPI AG

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